WebPTX- and CDDP-induced ocular toxicity is extremely rare and usually irreversible. The clinical manifestations mainly include abnormal vision, hemianopia, photopsia, visual … WebCisplatin (applies to cisplatin) ocular toxicity. Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance. Optic neuritis, papilledema, and cortical blindness have been reported in patients receiving standard recommended doses of cisplatin injection. Blurred vision and altered color perception have ...
HIGHLIGHTS OF PRESCRIBING INFORMATION - Food and …
Web5.7 Ocular Toxicity . 5.8 Secondary Malignancies . 5.9 Embryo -Fetal Toxicity . 5.1 0 Injection Site Reactions . 6 ADVERSE REACTIONS . ... x Neph ro toxicity: cisplatin for i njection can cause se vere renal toxicity, incl uding acute renal failure. Severe renal toxicities are dose- related and cumulative. WebFeb 11, 2024 · Mannitol for the prevention of cisplatin-induced nephrotoxicity: A retrospective comparison of hydration plus mannitol versus hydration alone in inpatient and outpatient regimens at a large academic medical center Show details Hide details Robert P Williams Brandon W Ferlas Paul C Morales Andy J Kurtzweil Journal of Oncology … impresoras instant ink
Ocular and orbital complications of intraarterial cisplatin. A …
WebAim: Cisplatin is a widely used and highly effective anti-cancer agent and one of the limiting side effects of cisplatin is ocular toxicity. Achillea millefolium , also known as yarrow, is … WebDec 13, 2024 · Also, ocular sections were evaluated histopathologically. Bromelain demonstrated a dose-dependent protective effect in cisplatin-induced toxicity by … WebJun 23, 2024 · Careful monitoring by audiometry should be performed prior to initiation of therapy and prior to subsequent doses of cisplatin. Vestibular toxicity has also been reported. (see section 4.8). ... deafness, ocular toxicity (including detachment of the retina), significant myelosuppression, untreatable nausea and vomiting and/or neuritis. An ... lithely pronunciation