WebRobinow syndrome . DVL1 and DVL3 encode segment polarity protein disheveled homolog DVL-1 (DVL1) and DVL-3, respectively, which are essential downstream mediators of Wnt signaling – specifically, the Wnt5a-ROR2 non-canonic pathway [ White et al 2015 , … WebJul 1, 2000 · Homo sapiens (human) progressive ankylosis-like protein (ENA - AAF88039) The Rat Genome Database (RGD) was established in 1999 and rapidly became the premier site for genetic, genomic, phenotype, and disease-related data generated from rat research.

ANKH transports PPi from cytosol to extracellular region

WebANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. WebMutation at the mouse progressive ankylosis (ank) locus causes a generalized, progressive form of arthritis accompanied by mineral deposition, formation of bony outgrowths, and … howard the cab driver

Role of the progressive ankylosis gene (ank) in cartilage ...

Webtransmembrane protein progressive ankylosis protein homolog (ANK). Although the etiology of apparent sporadic CPPD is not well-established, mutations in the ANK human gene (ANKH) have been shown ... Webprotein, affecting the levels of pyrophosphate in the extracellular matrix. Other Names for This Gene • ANK • ANKH_HUMAN • ankylosis, progressive homolog (mouse) • FLJ27166 • HANK • MANK • progressive ankylosis protein • SLC62A1 Additional Information & Resources Tests Listed in the Genetic Testing Registry WebAnkylosis protein (Ank), which transports intracellular inorganic pyrophosphate (PP (i)) to the extracellular milieu, is expressed by hypertrophic and, especially highly, by terminally differentiated mineralizing growth plate chondrocytes. howard theatre washington