WebMar 27, 2024 · Long-chain or sphingoid bases, of which sphingosine is typical, are the basic elements and are the simplest possible functional sphingolipids. They vary in chain-length and in the presence of various functional groups including double bonds of both the cis - and trans -configuration at different locations in the aliphatic chain. WebSphingolipids were named after the mythological sphinx because of their enigmatic nature. Sphingolipids, like the sphinx, are composed of diverse subunits: an amino diol, sphingosine, bound to a fatty acid by an amide linkage, and a polar head group. Perhaps the best known sphinx is the Great Sphinx of Giza.
21.4: Biosynthesis of Membrane Sphingolipids - Biology LibreTexts
WebThe sphingolipid metabolic pathway and the glycerophospholipid metabolic pathway was considered a crucial signaling pathway by Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. In addition, phosphatidylcholine and sphingomyelin were considered as hub metabolites. WebMay 18, 2024 · Ceramides are a type of sphingolipid (SL) that have been shown to play a role in several metabolic disorders. Here, the authors investigate the effect of SL-production by gut Bacteroides on host ... gotham time period
Biological functions of sphingomyelins - PubMed
WebSphingomyelin is an abundant sphingolipid in cellular membranes: its hydrolysis releases ceramide and phosphocholine and several stimuli are known to activate sphingomyelin … WebAug 3, 2013 · This review discusses the role of the sphingolipid metabolic pathway in diabetes, Alzheimer's disease, and hepatocellular carcinoma, with a special emphasis on … WebSep 5, 2024 · The analysis of sphingomyelin-metabolizing enzymes, the development of specific inhibitors, and advanced mass spectrometry have all provided insight into the … gotham tipografia