WebNov 10, 2016 · Localised scleroderma causes one or more patches of hard skin. There are different types. The common plaque type usually causes no problems (apart from sometimes an unsightly appearance) and tends to fade in time. The linear type can cause problems to underlying tissues such as muscles and bones. Often no treatment is needed … WebFeb 2, 2024 · Systemic sclerosis. Systemic sclerosis (SS) is an autoimmune disorder that causes atypical growth of connective tissues. Connective tissue gives your tissues (organs and muscles) strength and ...
Diagnosis and treatment of scleroderma - PubMed
Weban autoimmune skin disease characterized by progressive hardening and induration of the skin and/or other structures, such as the subcutaneous tissues, muscles, and internal organs. triad. autoimmunity. … WebSystemic sclerosis (systemic scleroderma) is a connective tissue disease associated with autoimmunity, vasculopathy, and fibrosis. The annual incidence is estimated to be 10 to 20 cases per 1 ... bit shift division
Treatment and prognosis of interstitial lung disease in …
WebScleroderma is a multisystem disorder characterized by skin thickening and vascular abnormalities. Causes of scleroderma remain mysterious. Immunologic abnormalities are suggested by the presence of characteristic autoantibodies such as ANA,anticentromere, and anti-Scl-70 antibodies. In addition to skin, the most commonly affected organs are ... WebMay 25, 2024 · Symptoms. Early indications of mixed connective tissue disease can include: General feeling of being unwell. This can include increased fatigue and a mild fever. Cold and numb fingers or toes (Raynaud's phenomenon). In response to cold or stress, your fingers or toes might turn white and then purplish blue. WebJan 27, 2024 · Diagnosis. Because scleroderma can take so many forms and affect so … data protection act 1998 is it still valid