Tsc2 cst

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August undefined, 2024

WebSep 18, 2015 · Transfection of TSC2 into p53 null cells replaced TSC2 and diminished Rheb at the lysosome, recapitulating cells with wt p53. ... They included rabbit anti-TSC2 (CST, 4308, 1:800), ... http://www.ybiotech.com.cn/ybiotech2012-Products-18645796/

Tuberin/TSC2 Antibody Cell Signaling Technology

WebApr 9, 2024 · Western blots were performed using the following antibodies at 1:1000 dilution unless otherwise indicated: phospho-p70 S6 kinase T389 (Cell Signaling Technology [CST] 9234 clone 108D2), p70 S6 kinase (CST 2708 clone 49D7), TSC2 (CST 4308 clone D93F12 and CST 3612), Rheb (CST 13879 clone E1G1R), GAPDH (CST 5174 clone D16H11), … WebFeb 4, 2024 · Protein lysates were separated by 4 to 12% bis-tris gels (Invitrogen) and then transferred to a polyvinylidene difluoride membrane. After the membranes were blocked, … csu cardsystem barueri

The mTORC1 Signaling Network Senses Changes in Cellular …

WebCell Signaling Technology (CST) allows the researcher to specifically inhibit tuberin/TSC2 expression using RNA interference, a method whereby gene expression can be selectively … WebMonoclonal Antibody for studying Raptor. Cited in 516 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously … WebPolyclonal Antibody for studying Tuberin/TSC2. Cited in 82 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Tuberin/TSC2 … csu cat reviewer

IMPDH inhibitors for antitumor therapy in tuberous sclerosis …

WebApr 20, 2024 · Of the five gross deletions in TSC2, three involved at least exons 40–46 of PKD1 (Fig. 3) resulting in the TSC2-PKD1 contiguous gene syndrome (CGS, MIM #600273), which were previously published 17. WebMay 17, 2024 · Loss-of-function mutations in TSC1 or TSC2, but not TBC1D7, give rise to TSC, a pleiotropic disorder with aberrant ... CST #5425) was used as a blocking solution … early repolarization treatmentWebMar 21, 2024 · TSC2 (TSC Complex Subunit 2) is a Protein Coding gene. Diseases associated with TSC2 include Lymphangioleiomyomatosis and Focal Cortical Dysplasia, … early repolarization vs pericarditis

"WebGene Location [ 1] 16p13.3. Pathway. PI3K/AKT1/MTOR. Gene. TSC2. TSC2 Mutation is present in 2.81% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, breast invasive ductal carcinoma, and conventional glioblastoma multiforme having the greatest prevalence [ 4 ]. " - Tsc2 cst

Tsc2 cst

Phospho-Tuberin/TSC2 (Ser939) Antibody - Cell Signaling …

WebMay 1, 2024 · Germline or mosaic loss-of-function mutations in either TSC1 or TSC2 give rise to the pleiotropic genetic ... 2.7 mM KCl, 0.1% Tween-20) plus 5% normal goat serum (NGS; CST #5425) was used as a blocking solution for 1 h at room temperature. Primary antibodies, p(S235/236)S6 (CST #4858, 1:400), fast skeletal Myosin (Sigma #M4276 ... WebJun 28, 2024 · To evaluate the knockdown efficiency of siRNA-TSC2 at the level of TSC2, high glucose-cultured podocytes were transfected with three different siRNA-TSC2 sequences. After TSC2 siRNA treatment for 24 h, Western blot analysis showed that transfection of TSC2 siRNA-1, TSC2 siRNA-2, and TSC2 siRNA-3 significantly reduced the …

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WebMonoclonal Antibody for studying Tuberin/TSC2. Cited in 288 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, … WebApr 8, 2014 · 在此过程中伴随着细胞的生长及胶原蛋白的更新，蛋白质合成在细胞生长中起重要logy作用[11明哺乳动物激酶(p7S6kin骨架的生长建立实验组织改建中的作用材料和方法试剂盒(大连抗体(CST白定量试剂盒(南京建成生物工实验分组动物模型的建立日本大耳白兔有实验动物均实验动物上作为实验侧使用牙科细 ...

WebPolyclonal Antibody for studying Tuberin/TSC2 (Ser939) phosphate. Cited in 51 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously … WebSanborn. Sep 2024 - Present8 months. Colorado Springs, Colorado, United States. Responsible for Operations of the Sanborn Mapping Business Unit. This includes ortho and oblique imagery technology ...

WebDec 2, 2024 · RIPK1 scaffold activity is known to have a pro-survival role in TNFα signaling. Najafov et al. discover an unexpected role for RIPK1 scaffold activity in mediating mTORC1 inhibition by AMPK during energetic stress. Mechanistic studies reveal that RIPK1 is involved in regulating TSC2 phosphorylation at Ser1387 by AMPK. Reduced phosphorylation of this … WebAug 24, 2012 · The tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 complex, which limits cell growth in response to poor growth conditions. Through …

WebTuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development (1). Mutations in either TSC2 or the related TSC1 …

WebPolyclonal Antibody for studying Tuberin/TSC2 (Ser1387) phosphate. Cited in 52 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. … csucc log inWebMonoclonal Antibody for studying Tuberin/TSC2. Cited in 288 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, Tuberin/TSC2 (D93F12) XP® Rabbit Monoclonal Antibody (CST #4308) is ready to ship. early republic eraWebApr 25, 2008 · AMPK phosphorylation of the TSC2 tumor suppressor contributes to suppression of mTORC1; however, TSC2-deficient cells remain responsive to energy stress. Using a proteomic and bioinformatics approach, we sought to identify additional substrates of AMPK that mediate its effects on growth control. csucc myschoolWebMutations in TSC2 can cause Lymphangioleiomyomatosis, a disease caused by the enlargement of tissue in the lungs, creating cysts and tumours and causing difficulty … earlyresolutionWeb1.1.2 主要试剂：DMEM-高糖培养基(Corning公司)；胎牛血清和EDTA-0.25% 胰蛋白酶(Gibco公司)；噻唑蓝(MTT)和二甲基亚砜(DMSO)(Ameresco公司)；氢氧化钠(NaOH)(北京化工厂)；雷帕霉素(rapamycin，Rapa)和羟乙基哌嗪乙硫磺酸(HEPES)(Sigma-Aldrich公司)；多聚甲醛和结晶紫(武汉塞维尔公司)；细胞周期与细胞凋亡检测试剂盒 ... early representations of the buddhaWebThe tumor suppressor genes TSC1 and TSC2 encode hamartin and tuberin, respectively (2,3). Hamartin and tuberin form a functional complex and are involved in numerous ... csuchWebPolyclonal Antibody for studying Tuberin/TSC2 (Thr1462) phosphate. Cited in 59 publications. Validated for Western Blotting. Highly specific and rigorously validated in … csu catholic church